The book Pharmacokinetic and Pharmacodynamic Data Analysis Concepts and Application is written by Johan Gabrielsson and Daniel Weiner. The fifth edition of Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications continue the central thesis of the first four editions: How do we move from data to knowledge most effectively? That can probably be done by exposing ourselves to a lot of data sets and real-life situations and solving these problems with pencil, paper, and a computer. Previous editions of the book have served as teaching aids for a number of basic and advanced courses within academia and at numerous pharmaceutical companies and regulatory agencies around the world. Therefore, substantial effort has been invested in the new pharmacokinetics and pharmacodynamics sections, including many new and updated case studies.
The five most common dysfunctions of a kinetics/modeler are lack of experience with exploratory data analysis; too much reliance on modeling software; data weighting; formula slavery; and, lack of holistic vision of the analysis-modeling process. The book serves to remedy parts of these dysfunctions and, in addition to being a repository for kinetic and dynamic data sets and modeling scenarios, it is intended to serve as a text on points to consider in biological data analysis in general. The audience continues to be industrial pharmacokinetics, pharmacologists, clinical pharmacologists, bioanalytical scientists, toxicologists, and scientists within academia and regulatory bodies.
- Teaches pharmacokinetic and pharmacodynamic concepts to undergraduate and graduate scientists.
- Meets requirements for Quantitative Pharmacology (Pharmacometry) courses.
- Uses over 100 real-life case studies.
- Encourages students to apply the methods outside the classroom.
- Requires very little calculation or statistical methods.
Topics of this Edition
- Chapter 1 1 – General Principles
- CHAPTER 2 – Pharmacokinetic Concepts
- CHAPTER 3 – Pharmacodynamic Concepts
- CHAPTER 4 – Modeling Strategies
- CHAPTER 5 – Elements of Experimental Design
- CHAPTER 6 – Pattern Recognition
- Pharmacokinetic Applications
Overview of Pharmacokinetic and Pharmacodynamic Data Analysis Concepts and Application
Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications teaches the analysis of everyday biological data at the undergraduate and graduate levels. Through numerous examples and over 100 tutorials, scientists learn how to use PK/PD seamlessly in a variety of practice areas, from simple plasma kinetics, multi-compartment models, nonlinear kinetics, plasma protein binding, pharmacodynamic models, turnover, receptor binding, functional adaptation and rebound, dose-response-time data analysis, cross-species scaling, and much more. Substantial effort has been invested in new pharmacokinetics and pharmacodynamics, including many new and updated case studies.
|Book Name||Pharmacokinetic and Pharmacodynamic Data Analysis Concepts and Application|
|Author of Book||Johan Gabrielsson, Daniel Weiner|