Computer Aided Pharmaceutics and Drug Delivery PDF Free Download

Computer-Aided Pharmaceutics and Drug Delivery An Application Guide for Students and Researchers of Pharmaceutical Sciences: This book written by Vikas Anand Saharan. You can download it freely in pdf format. I had the opportunity to learn computer applications for the first time in my school days, in the 1980s, when I had learned a little programming in DOS and what I remember most is playing Pac-Man when our teacher was not around. U.S. I did not have any computer courses in our Bachelor of Pharmacy program. In 1999–2001, I, as a student of the Master of Pharmacy Program, did a complete course on computers at NIPER (Mohali).

We, the students of the graduate program, had received hands-on training from professors not only from the computer science department but also from other departments such as pharmacy, pharmaceutical analysis, pharmaceutical chemistry, and pharmacology. We were taught and trained in various computer applications such as chemical structure drawing, molecular modeling, information retrieval, reference management, Excel applications in data handling and visualization, communication tools, and many others. . At the time, we were curious if all that training would ever be of any use in formulation development. But now, after some 20 years of experience in the field, I can say with confidence that our reliance on computers has increased tremendously to design quality formulations, in silico ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) predictions, and automation. . manufacturing, laboratory and analytical procedures.

Advances in computer-aided drug design (CADD) and the availability of three-dimensional structures of polymers, receptors, and other macromolecules have allowed formulation scientists to explore drug-polymer interactions in silico for drug targeting, drug control, and drug targeting. of drug release and other applications. Increased ethical concerns in animals and humans have also propagated the in silico characterization of ADMET by eliminating/reducing the use of animals/humans. Computer simulations have provided new ways to discover the pharmacokinetics/pharmacodynamics of new molecules in whole organisms, isolated tissues, cells, proteins, and genes. Data collection and maintenance is now very easy through electronic notebooks and numerous data storage options such as cloud storage, thanks to the ultra-high-speed of the Internet, search engines, and databases that have facilitated the process of retrieving academic literature. Artificial intelligence, robotics, big data (omics, chemical and clinical), IoT and health devices/applications are accelerating innovative computing applications in drug design, manufacturing and distribution. Computational approaches, statistical and molecular modeling have radically transformed the pharmaceutical industries’ dosage form development and drug delivery programs through experimental design and quality predictions through artificial intelligence (AI)-based software. . The concept of QbD (Quality by Design) has emerged as an interesting application of computers for the development of formulations. DoE (Design of Experiments) and process/formulation optimization have been made much easier with the help of software and expert systems.
This book Computer-Aided Pharmaceutics and Drug Delivery (CAPDD) explores the role of computers, software, databases, artificial neural networks, expert systems and information technologies in the fields of pharmaceutical formulation development, manufacturing, drug administration, biopharmaceutical and pharmacokinetic characterization and pharmaceutical analysis. This book is intended to meet the curricular requirements of pharmacy undergraduate and graduate students. Formulation scientists and research scholars find few resources on computer applications outside of the primary literature. Mid-career scientists found it more difficult to deal with the problem of a dearth of books on this topic. This book also satisfies the requirement of research scientists and academics to present the most up-to-date computer applications in a very lucid way so that the learning curve is somewhat shallow. Extensive applications of computers in formulation design and characterization are provided as examples, case studies, and illustrations. Brief reviews of software, databases, and expert systems have been added to pique readers’ interest and inspire them to apply these tools to develop novel formulations for effective drug delivery.

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