Advances in Pharmaceutical Sciences V.7: This book is written by David Ganderton, Trevor Jones, and James McGinity. You can download it freely in pdf format. Like its predecessors, Volume 7 of Advances in Pharmaceutical Sciences presents critical appraisals of current research and development in selected fields of pharmaceutical technology. It reflects, in particular, two vital activities for the industry. The first is the provision of a better understanding of well-established processes. This provides both a justification for further exploitation and a secure basis for quality management. The contributions of Rowe, Roberts, and Kristensen, all world authorities in the field of powder technology, exemplify this principle with important contributions that displace much of the empiricism associated with powder characterization and agglomeration.
The second great contribution of pharmaceutical technology lies in the administration of refined drugs. This is based on a mastery of physical-chemical principles that are then related to clinical practice through pharmacokinetics. The first part of this sequence is illustrated in Nairn’s comprehensive review, which assesses the considerable contribution of coacervation techniques, and the second in Urtti’s account of the pharmacokinetics of ocular drug delivery. These accounts provide a solid foundation for rational product development and future invention.
|Book Name||Advances in Pharmaceutical Sciences V.7|
|Author of Book||David Ganderton, Trevor Jones, and James McGinity|
Overview of Advances in Pharmaceutical Sciences V.7According to David Ganderton, Trevor Jones, and James McGinity, the vast majority of drugs, when isolated, exist as crystalline or amorphous solids. Subsequently, they can be ground (crushed) and/or mixed with other inactive solids (excipients) and finally filled into capsules or compacted to form tablets. The crushing and compaction processes involve subjecting the materials to efforts that cause their deformation. The reaction of the material to the deformation stress, ~a, depends on both the mode of deformation and the mechanical properties of the material.
Topics of this Edition1 The mechanical properties of powders
2 Kinetic aspects in the design of prolonged action ocular drug delivery systems
3 Coacervation-phase separation technology
4 Particle agglomeration
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